Views: 0 Author: Site Editor Publish Time: 2021-11-16 Origin: Site
Baidu data survey found that in recent years, in terms of efficacy, there has been a new and emphasized function - cell regeneration and repair, with a growth rate of 41%. In the natural cosmetic raw material market, Centella asiatica extract has become a "hot player" and can be called "the leader of the repair industry".
According to a Mintel survey report, Centella asiatica extract has become one of the increasingly popular and innovative skin care ingredients in the Korean beauty industry. It is mainly used in scar repair products and is considered to have the ability to help the skin Heals wounds and relieves inflammation.
Figure: Top 3 share of Centella asiatica extract in skin care products in 2016-2018 (Data source: Mintel)
Centella asiatica (L.) Urban, also known as Lei Gonggen, is native to India and is now widely distributed in tropical and subtropical regions of the world. In my country, it is mainly distributed in the provinces south of the Yangtze River. Centella asiatica has been used as a medicinal herb for thousands of years in my country, and traditional Indian medicine also regards it as a good medicine for healing wounds.
Cosmetics mainly use the dried whole grass of Centella asiatica, and its main active ingredients are madecassoside, madecassoside, madecassoside and madecassolic acid; among them, madecassoside and madecassoside belong to triterpenes Saponins, asiatic acid and madecassic acid are triterpene acid compounds; in addition, Centella asiatica extract also has an important component TECA, which is a high-purity 3 terpenoids (Centella asiatica) in Centella asiatica extract. glycosides, asiatic acid and madecassolic acid). These ingredients give Centella asiatica extract scar repairing, anti-inflammatory, anti-allergic skin care benefits.
Madecassoside can stimulate the proliferation of fibroblasts and activate the SMAD signaling pathway, increase the production of type I collagen, and thus have the activity of healing wounds, and at the same time can reduce the formation of stretch marks  . Centella asiatica extract can significantly promote the deposition of extracellular matrix proteins, it can promote the proliferation of fibroblasts, increase the synthesis of collagen, reduce the activity of metalloproteinases, thereby increasing the deposition of collagen and intracellular free protease amino acid levels .
Figure: Centella asiatica extract promotes collagen synthesis
Figure: Repair of scars with Centella asiatica extract gel
In vitro experiments found that TECA can inhibit the inflammatory response induced by LPS, and can effectively reduce the level of IgE and the release of inflammatory cytokines (IgE can induce the activation of mast cells and release a variety of allergic mediators, such as cytokines, histamine, etc.). Studies have shown that TECA can inactivate macrophages in the skin, thereby reducing skin inflammation and atopic responses . Therefore, Centella asiatica extract can be used in cosmetics as an anti-inflammatory and anti-allergic natural ingredient to relieve facial acne, redness, allergies and other symptoms.
Figure: Anti-inflammatory mechanism of Centella asiatica extract
we focuses on the research and development of natural cosmetic raw materials, and has customized 4 specifications of Centella asiatica extract for cosmetic customers: 10% Centella asiatica total glycosides (white), 90% Madecassoside, 36 -44% glycosides + 54-66% acid (95% TECA), 10% centella asiatica total glycosides (light yellow).
Good water solubility and alcohol solubility, clear and transparent after dissolving, no precipitation after long-term storage;
The powder is light in color and suitable for use with makeup.
Centella asiatica extract Centella asiatica extract
Plant source: Centella asiatica dried whole grass
INCI name: Centella asiatica (CENTELLA ASIATICA) extract
English INCI name: CENTELLA ASIATICA EXTRACT
Solubility: water-soluble - 10% centella asiatica total glycosides (white), 90% madecassoside, 10% centella asiatica total glycosides (light yellow); alcohol-soluble - 36-44% centella asiatica glycoside + 54-66% centella asiatica acid (95% TECA)
Additive dosage: 10% Centella asiatica total glycosides: 0.1-1%
90% Madecassoside: 0.1-0.2%
36-44% glycoside + 54-66% acid: 0.1-0.5%
Applicable dosage forms: facial cleanser, toner, essence, lotion, cream, gel, eye cream, etc.
Application effect: scar repair, anti-inflammatory and anti-allergic
How to use: Dissolve the product in water or alcohol solvent and add it to the cosmetic system before emulsification.