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Yohimbine Extract Yohimbine Hydrochloride8%-98% Johimbine 8%

Product Name:Yohimbe Extract Yohimbine HCL
Specification:8%
CAS:65-19-0
Appearance:Brown Yellow Powder
Detection method:HPLC
Molecular formula:C21H26N2O3
Molecular weight:390.91
Taste:Slightly fragrant, slightly bitter
Solubility:Easily soluble in , soluble in ethanol, slightly soluble in water
Availability:
Quantity:
  • XJM2201
  • XJM
  • 014
  • Yohimbine Hydrochloride8%-98% Johimbine 8%
  • Brown yellow to white powder
  • HPLC and UV
  • 65-19-0
  • 1%-98%
  • Kosher HALAL GMP ISO2000
  • 80-200MESH
  • Nuciferine Flavones
  • Pharm grade or food grade
  • Solvent Extraction
  • 2years
  • Aluminum foil bag or drum packing
  • Avaliable

Yohimbine hydrochloride is an α2-adrenergic receptor antagonist and increases the firing rate of the locus coeruleus with a resultant increase in sympathetic outflow (Redmond, 1987). Oral and intravenous yohimbine causes an increase in MHPG and blood pressure in healthy human subjects (Charney et al., 1982d; Goldberg et al., 1986). Depressed patients demonstrate an increased cortisol and blood pressure response to intravenous yohimbine compared with healthy subjects, while plasma MHPG is not significantly different between the two groups of subjects (Heninger et al., 1988). The effects of acute or chronic antidepressant treatments on the neuroendocrine or behavioural responses to yohimbine in depressed patients have not been studied.

Yohimbe

Function of Yohimbine Extract Yohimbine Hydrochloride8%-98% Johimbine 8%:

Yohimbine exerts a stimulant effect on mood and may increase blood pressure at higher doses. Yohimbine may also have mild antidiuretic action, possibly due to release of antidiuretic hormone.

Yohimbine hydrochloride is a pre-synaptic alpha 2-adrenergic blocking agent. The exact mechanism for its use in impotence has not been fully elucidated. However, yohimbine may exert its beneficial effect on erectile ability through blockade of central alpha 2-adrenergic receptors producing an increase in sympathetic drive secondary to an increase in norepinephrine release and in firing rate of cells in the brain noradrenergic nuclei.Yohimbine-mediated norepinephrine release at the level of the corporeal tissues may also be involved. In addition, beneficial effects may involve other neurotransmitters such as dopamine and serotonin and cholinergic receptors.

Yohimbine hydrochloride is white to slightly yellow powder

Indole alkaloid with α2-adrenergic blocking activity. Mydriatic. Used in the treatment of neurological disorders.

alpha adrenergic blocker, mydriatic, antidepressant

vasodilator, neuromodulator

a2-adrenergic antagonist, used for erectile dysfunction

Erectile dysfunction & Mydriatic agent

An α2-adrenoceptor antagonist

Pharmacological probe for the study of a2-adrenoceptor.

Application of Yohimbine Extract Yohimbine Hydrochloride8%-98% Johimbine 8%:

Yohimbine hydrochloride is an α2-adrenergic receptor antagonist. It blocks the central α2-adrenegic receptors in the brain, thus preventing and reducing the effects of xylazine, an α2-adrenergic agonist. The sedative effects and respiratory depression that accompany xylazine administration are both antagonized and reversed by yohimbine. Yohimbine hydrochloride also produces an antidiuretic effect, and increases heart rate and blood pressure.

Biochem/physiol Actions

Yohimbine is derived from the Coryanthe yohimbe tree cortex. It is an alkaloid. Yohimbine hydrochloride is an α2-adrenergic receptor antagonist. It blocks the central α2-adrenergic receptors in the brain, thus preventing and reducing the effects of xylazine, an α2-adrenergic agonist. The sedative effects and respiratory depression that accompany xylazine administration are both antagonized and reversed by yohimbine. Yohimbine hydrochloride also produces an antidiuretic effect, and increases heart rate and blood pressure. It is useful in treating erectile dysfunction and promotes sexual functioning.

Veterinary Drugs and Treatments

Yohimbine is indicated to reverse the effects of xylazine in dogs, but it is being used clinically in several other species as well.

Yohimbine may be efficacious in reversing some of the toxic effects associated with other agents (e.g., amitraz) and can be used prophylactically before amitraz dips.


yohimbine

International Commercial Terms(Incoterms):FOB,EXW,CFR,CIF,DAT,FAS,DDP,DAP,CIP,CPT,FCA

Terms of Payment:LC.T/T.D/P.Trader assurances.western unions.moneygrams.paypal

Average Lead Time: 1-7days after receiving your payment.

Peak Season Lead Time: within 15 workdays

Off Season Lead Time: within 15 workdays

Number of Foreign Trading Staff:10 peoples

Main Markets:North America.South America.Southeast Asia.Africa.Oceania.Eastern Asia.Western Europe

Export Year:2018

Nearest Port:Shanghai

Import & Export Mode:Have Own Export License

R&D Capacity:OEM

Number. of R&D Staff:10 peoples

Number. of Production Lines:3 lines

Annual Output Value:US$5 Million - US$10 Million

Number of factory employees:more than 200peoples


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